或者有别的有空有闲XJBC的,能不能花点时间组织一下。
俺实在没有时间搞。
动物养殖业已经用了几十年了(1944年开始的roxarsone),如果有问题早就大了去了,但是不排除砷累积和过量使用的长期后果。
对于不同用途,用量也不一样。链接见此
http://www.drugs.com/pro/3-nitro.html最大用量大约 0.2g/公斤饲料。 连续用不超过6天 (no more than 6 days)。
在动物体内代谢期5天。屠宰前5天不能给药。
老鼠的LD50量为 367毫克/公斤。
具体数据参见
http://www.wikigenes.org/e/chem/e/5104.html不过FDA前两年的研究表明在鸡肝内发现,用此添加剂的和不用的对比,鸡肝内的砷含量相比增加,虽然FDA用的是very low,但是依然引起鸡肝是否安全的担心。
I'm looking at the study
and it suggests that while there was a mean - overall mean concentration
below the tolerance of 2000 parts pe
r billion, some of these chicken
livers seem to have as much as 2900 parts per billion.And that seems way above the tolera
nce level. Doesn't that mean these
chicken livers are unsafe?
FDA具体的文件链接,和关于roxarsone的问答
http://www.fda.gov/downloads/NewsEvents/Newsroom/MediaTranscripts/UCM258791.pdfhttp://www.fda.gov/AnimalVeterinary/SafetyHealth/ProductSafetyInformation/ucm258313.htm但是辉瑞于2011年自愿停止下属的生产厂销售roxarsone(在美国)
(Earlier this year, Pfizer voluntarily agreed to stop selling 3-Nitro, an arsenic-containing product for food animals. But Pfizer has given no indication that it will stop marketing the product in as many as 11 other countries where it has been sold, or that it will stop selling other FDA-approved arsenic feed additives.)
国内也有在研究这个砷添加剂的危害的。其中有一个是科学院地理和自然资源所的关于砷的环境污染的文章。
Concentrations of additive arsenic in Beijing pig
feeds and the residues in pig manure
Resources, Conservation and Recycling 45 (2005) 356–367
http://www.prairieswine.com/pdf/34614.pdf此文章中提到的一个数据,涉及的是累积的用量,听上去你就会觉得这个后续问题可能不小。
The quantities of arsenic input through pig feeds in the period of 1980–1999 wasestimated based on statistical data from Beijing Bureau of Statistics (1980–2000) and theanalytical data in this study, then were shown in Fig. 2. Over the last 20 years, the sum of arsenic input through pig feeds probably exceeded 126.5 t in Beijing
EPA也有一个poster,链接见
http://www.epa.gov/esd/pdf-ecb/348ecb03.pdf但是它似乎是只看roxarsone的,比较起来应该没有太大意义。
俺的结论,鸡肝猪肝任何肝之类的不吃为妙。