http://www.jurology.com/article/S0022-5347%2815%2904714-X/abstract
http://xys.org/forum/db/12/31/6.html
An effect of anticholinergic treatment on the results of the procedure cannot be completely excluded. However, it will probably only reduce and not eliminate a reflex response as it targets the postganglionic neurons, whereas nerve reinnervation will be pre-ganglionic in the bladder. Furthermore, and most importantly, when interpreting our data, only 4 of 10 patients included received anticholinergic treatment at baseline and 3 continued on followup. There was no effect of treatment in the patients not receiving anticholinergics. Therefore, anticholinergic treatment cannot explain the observed lack of effect of the somato-autonomic reflex arch on neurogenic bladder dysfunction. Furthermore, data on bowel function from the same patients have recently been published and revealed similar disappointing results.
【简译:从原理上说,抗胆碱治疗不大可能会影响肖氏手术效果……】而且,最重要的是,看看我们的数据,10名患者中,只有4名术前接受收抗胆碱治疗、3名术后继续。未接受收抗胆碱治疗的患者同样手术无效。因此,抗胆碱治疗不能解释所观察到的躯体-自主神经反射弧治疗神经源性膀胱功能障碍的手术无效。