送交者: Yush 于 2005-10-26, 10:17:37:
回答: 院士候选人肖传国撒了一个弥天大谎 由 jonhan 于 2005-10-25, 23:48:19:
“我就拿肖候补院士的两篇临床试验文章来驳一驳看那些临床试验是怎样的破绽百出”：
请把[3]也算上，特别是其中的“post-void residual was 200 cc's”与[1]中的31ml、[2]中的23.67ml明显不同。另外，不知道这个200毫升残留量能否意味着“有效”。
[4]中有对前人工作的回顾，肖作为第二作者算是自打嘴巴（“在国际上首先提出并证实了‘人工体神经－内脏神经反射弧’理论”）。
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2003
[1] Xiao CG, Du MX, Dai CP, et al. An artificial somatic-central nervous system-autonomic reflex pathway for controllable micturition after spinal cord injury: Preliminary results in 15 patients JOURNAL OF UROLOGY 170 (4): 1237-1241 Part 1 OCT 2003 Times Cited: 3
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detrusor pressure was steady at 20 to 25 cm water when infusing volume reached 250 to 300 ml.
residual urine decreased from 332 to 31 ml
mean detrusor pressure +/-SD decreased from 88+/-9 to 67+/-3.5 cm water (p
12/14 areflexic bladder
bladder capacity increased from 117.28 to 208.71 ml
post-void residual urine decreased from 99.36 to 57 ml
mean maximum detrusor pressure increased from 18.35 to 32.57 cm (50 to 60 cm H2O in normal controls)
5/6 hyperreflexic bladder
bladder capacity increased from 94.33 to 177.83 ml,
residual urine decreased from 70.17 to 23.67 ml
The high detrusor pressure (Pdet) decreased from a mean of 61.50 to 47 cm H2O.
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2005-2
[3] Kelly CE, Xiao CG, Weiner H, et al. Creation of a somatic-autonomic reflex pathway for treatment of neurogenic bladder in patients with spinal cord injury: Preliminary results of first 2 USA patients JOURNAL OF UROLOGY 173 (4): 307-308 1132 Suppl. S APR 2005
http://www.urotoday.org/prod/contents/confreport/article.asp?cat=confReport&sid=184&tid=398&aid=2700
Abstract #1132
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At last follow-up (15 months) L5 stimulation caused a detrusor contraction of 59 cm H20, a Q max of 8 cc/sec and no DESD. Voided volume was 150cc and post-void residual was 200 cc's
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[4] Sievert KD, Xiao CG, et al. Voluntary micturition after intradural nerve anastomosis. Urologe A. 2005 Jul;44(7):756-61. [Article in German]
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15959611