I have a question for your guys. Miller's structure obviously makes more sense biochemically. But I don't understand how Shi could have got it wrong. At 3.6 A, can one tell the difference betwee a Glu from a Trp? Those are the residues in the middle of the stretch in helix 6 in their respective structures. The electron density should be drastically different between these two. In the Shi's paper, they highlighted Glu208. If they are wrong, that should have been Trp202 (or an Ser203?). How can they be this wrong or you think they didn't bother to re-check the side chains against the electron density data? Thanks for any insights.