文献:最早在截瘫病人用nerve rerouting重建膀胱控制的是瑞典1980发表的两例


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送交者: PoohHunny2 于 2009-11-29, 00:20:07:

From Sahlgren Hospital at Goteborg and Lund University. 1978年投稿1980年刊出的两例截瘫病人手术报告,通过接驳T12去S2/S3,1年以后完全恢复尿意并自主排尿。

Spine (Phila Pa 1976). 1980 Jan-Feb;5(1):37-41.

Reconstruction of afferent and efferent nervous pathways to the urinary bladder in two paraplegic patients.
Carlsson CA, Sundin T.

Based on animal experiments, spinal root anastomoses were performed in two paraplegic patients who had traumatic lesions of the conus medullaris. The aim was to reinnervate the paralyzed urinary bladder. At operation, the functioning T12 nerve roots above the lesion were transected and anastomosed bilaterally to the S2 and S3 ventral and dorsal roots emerging from the injured cord area. About 1 year postoperatively, both patients demonstrated restoration of the micturition reflex as recorded in the cystometrogram. Both patients could feel the urge to void, could initate micturition voluntarily, and could empty their bladders satisfactorily. The patients' relatively good bladder functions were the result of either regeneration of the newly constructed nervous pathways or spontaneously developed reflex bladders in partial upper neuron lesions.

PMID: 7361197 [pubmed - indexed for medline]




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