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(WO/2005/007093) USES OF IL-12 IN HEMATOPOIESISBiblio. Data Description Claims National PhaseNoticesDocuments Latest bibliographic data on file with the International Bureau
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Pub. No.: WO/2005/007093 International Application No.: PCT/US2004/021710
Publication Date: 27.01.2005 International Filing Date: 06.07.2004
IPC: A61K 38/20 (2006.01), C07K 14/54 (2006.01)
Applicants: UNIVERSITY OF SOUTHERN CALIFORNIA [us/us]; 3716 South Hope Street,, Suite 313, Los Angeles, CA 90007-4344 (US) (All Except US).
ANDERSON, W. French [us/us]; (US) (US Only).
ZHAO, Yi [cn/us]; (US) (US Only).
CHEN, Tingchao [cn/us]; (US) (US Only).
Inventors: ANDERSON, W. French; (US).
ZHAO, Yi; (US).
CHEN, Tingchao; (US).
Agent: LUO, Y., Jenny; Hogan & Hartson L.L.P., Biltmore Tower, 500 South Grand Av., Suite 1900, Los Angeles, CA 90071 (US) .
Priority Data: 60/485,170 03.07.2003 US
03148180.9 04.07.2003 CN

Title: USES OF IL-12 IN HEMATOPOIESIS
Abstract: Embodiments of the present invention are directed to uses of Interleukin-12 (IL­12) in enhancing or stimulating hematopoietis to yield hematopoietic recovery in a mammal in need. Particular embodiments of the invention are directed to uses of IL-12 as an adjuvant therapy to alleviate the hematopoietic toxicities associated with one or more treatment regimens used to combat a disease state. Other embodiments include uses of IL-12 to ameliorate various hematopoietic deficiencies. Still other embodiments are directed to uses of IL-12 for in-vivo proliferation of hematopoietic repopulating cells, hematopoietic progenitor cells and hematopoietic stem cells. Other disclosed embodiments are directed to uses of I1-12 for bone marrow preservation or recovery.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Org. (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (EAPO) (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)