他们的Primary Outcome Measures是Reproducible bladder contraction


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送交者: 羽矢 于 2011-03-03, 00:39:45:

回答: 谁知道他们定出的clinical significance是什麽吗? 由 cornbug 于 2011-03-03, 00:11:40:

引用:
http://clinicaltrials.gov/show/NCT01096459
Primary Outcome Measures:
* Reproducible bladder contraction [ time frame: 6 to 24 months post procedure ] [ designated as safety issue: yes ]
The primary aim of this study is reproducible bladder contraction of 15cm/H20 or more with scratching the cutaneous dermatome and no significant contraction with stimulation of the non-operated side.

其实他们自己也搞不清楚,在一年结果论文中糊弄:

引用:
A difficult aspect of this study is how success should be defined.... Does the benefit of the procedure outweigh the inherent risks, particularly to the lower extremity? Is success defined as eliciting a detrusor contraction with stimulation of the dermatome? If this is the definition of success, then this surgery clearly works for the majority of patients.

引用:
http://www.xys.org/xys/ebooks/others/science/dajia11/xiaochuanguo133.txt




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