if your paraphasing is accurate, this really confused me.



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送交者: xj 于 2005-1-11, 18:11:16:

回答: 女人长寿 心“好”是关键 (ZT) 由 Latino2 于 2005-1-11, 17:12:06:

I am not sure what the authors meant about the heart function. It looks like they are doing fittness test (e.g., treadmill test) accompanied by calcification measurement in aterials (e.g. coronary artery calcification), and ultrasound test (or echocardiography). Doppler echocardiography can measure blood flow in heart, which I assume what they are talking about 抽动的能力. For example, ejection fraction.

Now the catch. It is well known that men have higher cardiovascular risks than women before women have menapause. After then, the cardiovascular risks in women climb really fast and are equivalent to those in men. There is overall probably ten years lag for women to catch up. This leads many hypotheses about hormone replacement therapy (HRT). As you may know, HRT has been shown some risks of stroke and cancers in woman health initiative study. More striking, some studies showed that the incident rates of myocardial infarction(MI), and subsequent congestive heart failure, are actually higher in women than in men after age 65. It seems that this is contradicting with the study's results.

It is well known that atherosclerosis can start as earlier as childhood (e.g., yellow strips, the lipid accumulation in large aterial vessels), and again women have that later than men do but the postmenopausal catch-up growth is quick. So I am not sure merely 250 people will have sufficient large life span and also enough sample size.



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