Schrödinger decided in 1933 that he could not live in a country in which persecution of Jews had become a national policy. Alexander Frederick Lindemann, the head of physics at Oxford University, visited Germany in the spring of 1933 to try to arrange positions in England for some young Jewish scientists from Germany. He spoke to Schrödinger about posts for one of his assistants and was surprised to discover that Schrödinger himself was interested in leaving Germany. Schrödinger asked for a colleague, Arthur March, to be offered a post as his assistant.

The request for March stemmed from Schrödinger's unconventional relationships with women: although his relations with his wife Anny were good, he had had many lovers with his wife's full knowledge (and in fact, Anny had her own lover, Hermann Weyl).[14] Schrödinger asked for March to be his assistant because, at that time, he was in love with March's wife Hilde.

Many of the scientists who had left Germany spent mid-1933 in the Italian province of South Tyrol. Here Hilde became pregnant with Schrödinger's child. On 4 November 1933 Schrödinger, his wife and Hilde March arrived in Oxford. Schrödinger had been elected a fellow of Magdalen College. Soon after they arrived in Oxford, Schrödinger heard that, for his work on wave mechanics, he had been awarded the Nobel prize.

In early 1934 Schrödinger was invited to lecture at Princeton University and while there he was made an offer of a permanent position. On his return to Oxford he negotiated about salary and pension conditions at Princeton but in the end he did not accept. It is thought that the fact that he wished to live at Princeton with Anny and Hilde both sharing the upbringing of his child was not found acceptable. The fact that Schrödinger openly had two wives, even if one of them was married to another man, was not well received in Oxford either. Nevertheless, his daughter Ruth Georgie Erica was born there on 30 May 1934.