Even after being diagnosed with cancer of the esophagus in 2010, Hitchens refused to turn to a deity or organized religion for comfort. He made it clear that if anyone ever claimed he had converted at the end of his life, it would be either a lie propagated by the religious community or an effect of the cancer and treatment that made him no longer himself.

"The entity making such a remark might be a raving, terrified person whose cancer has spread to the brain. I can't guarantee that such an entity wouldn't make such a ridiculous remark, but no one recognizable as myself would ever make such a remark," he said.