RCT design to test the effectiveness of an intervention

送交者: cornbug 于 2012-01-13, 11:31:10:

回答: there is some confusion here. 由猎人于 2012-01-13, 11:00:38:

with one year follow up. Subjects will go though a test for their responses. Measure is the score based on the symptoms developed during the test that cannot practically be measured objectively. The scoring system has been validated in several peer reviewed papers from different institutions. Since it is subjective in nature, to make it less subjective and consistent, a blinded person will be used to give the scores upon reported symptoms and the signs of the symptoms.

The change scores are the difference in endpoint scores before and after the intervention. For an longitudinal analysis over time, repeated measures ANOVA will be used.

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I am now getting your point - blackbox (461 bytes) 2012-01-13, 13:02:42 (641251)
- if I remember correctly, these are all called "quality (control) study" - 猎人 (334 bytes) 2012-01-13, 13:41:08 (641256)
  - Questionare could collect rating or scale data, - blackbox (43 bytes) 2012-01-13, 16:11:09 (641283)
    - Questionare is OK, for the endpoint score - cornbug (68 bytes) 2012-01-13, 16:41:34 (641294)
      - I don't understand this"...development of symptoms....." (无内容) - 猎人 (0 bytes) 2012-01-13, 19:05:55 (641310)
        
        The severity is a function of exposure time. (无内容) - cornbug (0 bytes) 2012-01-13, 23:25:16 (641333)
      - it may more sense by reading this and the one below - blackbox (176 bytes) 2012-01-13, 18:18:30 (641306)
- I have never been involved in a clinical trial - cornbug (929 bytes) 2012-01-13, 13:32:55 (641254)
  - without much details re: type of intervention and outcome, - 猎人 (318 bytes) 2012-01-13, 14:43:13 (641261)
    - ha, that is what I can say - cornbug (736 bytes) 2012-01-13, 15:05:14 (641264)
      - currently, is there a measure to manage this condition? - 猎人 (86 bytes) 2012-01-13, 15:20:59 (641267)
        
        then your procedure and/or med is to abolish the attack - 猎人 (2058 bytes) 2012-01-13, 17:48:57 (641305)
        
        suvival analysis and QoL are additional measures - cornbug (38 bytes) 2012-01-13, 16:38:39 (641292)
        
        Every thine has a psych impact, but not serious. - cornbug (302 bytes) 2012-01-13, 16:34:05 (641290)
        
        Yes. She will do and get 5-10% of her salary. (无内容) - cornbug (0 bytes) 2012-01-13, 16:23:38 (641286)
        
        triggered externally. (无内容) - cornbug (0 bytes) 2012-01-13, 16:21:36 (641284)
        
        is the condition persistent or episodic? (无内容) - 猎人 (0 bytes) 2012-01-13, 16:07:19 (641282)
        
        still don't feel - blackbox (386 bytes) 2012-01-13, 16:04:08 (641281)
        
        what do u claim about your procedure compared with the med? - 猎人 (124 bytes) 2012-01-13, 15:54:43 (641278)
        
        Yes. Medications with temporary relief and side effects. - cornbug (20 bytes) 2012-01-13, 15:28:48 (641270)
few comments - 猎人 (817 bytes) 2012-01-13, 12:35:47 (641245)
- Thanks. I have never had a cell. (无内容) - cornbug (0 bytes) 2012-01-13, 12:57:53 (641250)
  - Oh man! you may have a loud voice and pair of sensitive ears. (无内容) - 猎人 (0 bytes) 2012-01-13, 13:12:35 (641252)
    - I am a bug with the sixth sense. (无内容) - cornbug (0 bytes) 2012-01-13, 13:39:30 (641255)

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